What are Telomeres and how it can fight the signs of aging?

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What are Telomeres?

Telomeres are the main responsible agent inside your body that protects your cell chromosomes from fusing with each other or rearranging.  Because of the presence of enough telomeres inside a person’s body they can prevent abnormalities that can lead to cancer. Once the telomeres are consumed inside the body, this is the time that your body starts deteriorating leading to the many signs of aging like saggy skin, lack of focus and other unsightly signs of aging. To keep it simple, telomeres are likes tips on the ends of your shoelaces, they are the ones responsible for making sure that your cells will not easily get destroyed and invaded by destructive occurrences inside the body.

( http://www.news-medical.net/life-sciences/Telomere-What-are-Telomeres.aspx)

The longer your telomeres are, and the higher the number inside the body means reduced signs aging and sickness, the shorter the telomeres the higher the number of diseases that can attack the body.

What you need to understand about Telomeres and Aging

Aging is the process of progressive functional loss of tissue function, it eventually leads to death. The body starts losing telomere, the aging process becomes faster and this will include the deterioration of blood cells, endothelial cells, hepatocytes, kidney epithelium, muscle cells and many others. The discovery of telomeres has been crucial in developing the stem cell solutions that are being provided today by International Stem cell clinics like Feeling Good At Any Age The One- Stop Rejuvenation Clinic to Turn Back Time.

 

Telomore Extension and Turning Back time using cultured human cells

Stem cell clinics are now offering ways to efficiently increase the length of human telomeres. Treatment of cells has been widely explored by researchers worldwide. Because of various research, they are now able to determine how to lengthen telomeres. For example, skin cells with telomeres that are lengthened are able to divide 40 times compared with the cells that remain untreated.

To turn back the internal clock, scientists and researchers are now lengthening the human telomeres by as much as 1,000 nucleotide- this means that human life can now be extended.

The newly developed techniques create an advantage on human cells, it is like putting a better engine on a vehicle and making sure that it will drive faster.  While treated cells will not divide indefinitely, it is now considered one of the most potent ways to lessen the signs of aging.

Increasing Telomeres to Treat the Diseases caused by Aging

Researchers were able to find several applications to lengthen the telomeres inside the body in several days through the process of culturing human cells and skin cells. This means that stem cell therapies are now shorter and the benefits can now be experienced faster compared before. The uses of these discoveries now lead to the prevention and treatment of diseases caused by aging. The studies about telomeres have improved stem cell therapies and would eventually lead to the treatment of accelerated aging in humans.

Signs of aging like diabetes and heart disease are on top of the potential benefits and uses of stem cell therapy.

The Harvard Study

In a recent study conducted by Ronald DePinho and a team of Harvard colleagues, they have experimented on mice to see what happens when they will shorten the telomeres of the mice.  This led to the breeding of genetically engineered mice that lacked the ability to create telomerase- and in their findings, the mice in the experiment quickly showed rapid and early symptoms of aging. After this, they injected the mice with telomerase enzyme- they want to slow down the process of aging and put it into normal levels.  The scientists were so astonished by the results, instead of aging slowly, the mice appeared to age backward, repairing themselves to the point of new neurons beginning to sprout in their brains.

This means that the mice were able to reverse the signs of aging and make themselves look even younger, despite experiencing the ravages of age earlier.

Just imagine the potential solutions that these solutions can provide. Imagine an 80-year-old being given an injection of the cells and rebuilding their physical health on their own and back to their rejuvenated self at age 25. There are still a lot of experimentations involved when it comes to humans, and more research needed to combat aging as a whole, but the discovery of telomeres is now one of the leading hopes of the stem cell therapy research.

Sources:

  • https://med.stanford.edu/news/all-news/2015/01/telomere-extension-turns-back-aging-clock-in-cultured-cells.html
  1. http://cdn.intechopen.com/pdfs-wm/40891.pdf
  2. http://physrev.physiology.org/content/88/2/557
  3. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583695/
  4. http://www.agnos.nl/downloads-2/files/BlascoStemCells2007.pdf
  5. http://biomedgerontology.oxfordjournals.org/content/66A/2/202.full
  6. Londoño-Vallejo JA. Telomeres, Epigenetis, and Aging. In: Tollefsbol TO, editor. Epigenetics of Aging. Springer Science+Business Media, LLC, 2010; pp. 205-226.

About the Author:

Kali Alaia is a digital marketer, strategist, researcher, and content provider.  The articles posted on this site is based on a number of medical journals and sources found online and are intended for educational purposes only. Any recommendations in here are not intended to replace the recommendation of your doctor. Always seek your attending physician before submitting to any suggestions posted on this website. The personal stories and content are curated as a way to inform.

 

 

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